What is the main term related to myxedema coma?

The main term related to myxedema coma is "myxedema." Myxedema coma is a severe and life-threatening condition that arises from untreated hypothyroidism, characterized by very low levels of thyroid hormone in the body. In this context, the term "myxedema" specifically refers to the thickening of the skin and other tissues that occurs due to the accumulation of mucopolysaccharides, which is a hallmark of severe hypothyroid conditions. Myxedema coma signifies a critical state where patients may experience a drastic decline in metabolic function, affecting multiple organ systems and requiring immediate medical attention.

The other terms do not relate directly to myxedema coma. Diabetes, for example, is a metabolic disorder characterized by high blood sugar levels and pertains to a different set of endocrine issues. Fatigue and weight gain can be symptoms associated with hypothyroidism, but they are not the primary defining terms for the condition itself. Focusing on "myxedema" allows for understanding the pathological state and its direct link to the underlying thyroid dysfunction.