Which chapter in ICD-10-CM contains codes with site and laterality designations?

The chapter in ICD-10-CM that contains codes with site and laterality designations is the one focused on diseases of the respiratory system. This chapter extensively categorizes various lung conditions and other respiratory ailments, allowing coders to specify the exact site of the condition within the respiratory system. Additionally, it applies laterality to conditions affecting paired organs, such as whether the condition is present on the right side, left side, or bilaterally. This specificity is critical for accurate coding, ensuring that healthcare providers can capture the precise nature and location of a patient's illness, which is essential for treatment, billing, and statistical analysis.

The chapters not selected either cover different categories of diseases or do not emphasize site and laterality in the same detailed manner as the chapter related to respiratory conditions.